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Mouse IL13RA1 Protein, hFc Tag

Mouse IL13RA1 Protein, hFc Tag

产品编号

KMP3838

别名

白细胞介素13受体亚基α1, IL13RA1 Protein, Mouse IL13RA1 Protein, hFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞介素13受体亚基α1, IL13RA1 Protein, Mouse IL13RA1 Protein, hFc Tag
Catalog NumberKMP3838
Product DescriptionThe Mouse IL13RA1 Protein(KMP3838) is produced in HEK293 Cells. A DNA sequence encoding the Mouse IL13RA1 (NP_598751.3) (Met1-Thr340) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameIL13RA1
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundInterleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight62.8 kDa

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