Mouse CCL20 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CCL20 Protein, His Tag

Mouse CCL20 Protein, His Tag

产品编号

KMP3823

别名

趋化因子配体20, CCL20 Protein, Mouse CCL20 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	趋化因子配体20, CCL20 Protein, Mouse CCL20 Protein, His Tag
Catalog Number	KMP3823
Product Description	The Mouse CCL20 Protein(KMP3823) is produced in Insect Cells. A DNA sequence encoding the Mouse CCL20 (O89093-1) (Met 1-Met 97) is expressed,with a C-terminal polyhistidine tag.
Molecular Name	CCL20
Species	Mouse
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 500mM NaCl, 10% Gly, pH7.4
Background	Chemokine (C-C motif) ligand 2 (CCL2) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A/CCL2 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A/CCL2 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A/CCL2 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL2 was shown to play a role in colorectal cancer (CRC) pathogenesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	9.3 kDa

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