Mouse Frizzled 2 Protein, hFc Tag
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产品编号
KMP3819
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别名
卷曲蛋白-2, Frizzled 2 Protein, Mouse Frizzled 2 Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 卷曲蛋白-2, Frizzled 2 Protein, Mouse Frizzled 2 Protein, hFc Tag |
Catalog Number | KMP3819 |
Product Description | The Mouse Frizzled 2 Protein(KMP3819) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Fzd2 (NP_065256.1) (Gln29-Leu168) is expressed with the Fc region of human IgG1 at the N-terminus. |
Molecular Name | Frizzled 2 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | FZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and characterized by facial dysmorphism and shortness of the upper extremities and first metacarpal bones, and heterozygous FZD2 mutations may be disease-causing for OMOD2. heterozygous de novo mutation (G434V) in the frizzled class receptor 2 (FZD2) gene in a patient with distinct facial features including hypertelorism, bilateral cleft lip/palate, short nose with a broad nasal bridge, microretrognathia, and bilateral shortness of the upper limbs, |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 44.2 kDa |