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Mouse Frizzled 2 Protein, hFc Tag

Mouse Frizzled 2 Protein, hFc Tag

产品编号

KMP3819

别名

卷曲蛋白-2, Frizzled 2 Protein, Mouse Frizzled 2 Protein, hFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias卷曲蛋白-2, Frizzled 2 Protein, Mouse Frizzled 2 Protein, hFc Tag
Catalog NumberKMP3819
Product DescriptionThe Mouse Frizzled 2 Protein(KMP3819) is produced in HEK293 Cells. A DNA sequence encoding the Mouse Fzd2 (NP_065256.1) (Gln29-Leu168) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular NameFrizzled 2
SpeciesMouse
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundFZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and characterized by facial dysmorphism and shortness of the upper extremities and first metacarpal bones, and heterozygous FZD2 mutations may be disease-causing for OMOD2. heterozygous de novo mutation (G434V) in the frizzled class receptor 2 (FZD2) gene in a patient with distinct facial features including hypertelorism, bilateral cleft lip/palate, short nose with a broad nasal bridge, microretrognathia, and bilateral shortness of the upper limbs,
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight44.2 kDa

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