Mouse CCL6 Protein, His Tag
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产品编号
KMP3818
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别名
趋化因子配体6, CCL6 Protein, Mouse CCL6 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 趋化因子配体6, CCL6 Protein, Mouse CCL6 Protein, His Tag |
Catalog Number | KMP3818 |
Product Description | The Mouse CCL6 Protein(KMP3818) is produced in HEK293 Cells. A DNA sequence encoding the Mouse CCL6 (P27784) (Met 1-Ala 116) is fused with a polyhistidine tag at the C-terminus. |
Molecular Name | CCL6 |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears to contribute to the macrophage infiltration that is independent of other CC chemokines. C10 is a prominent chemokine expressed in the central nervous system in experimental inflammatory demyelinating disease, also acts as a potent chemotactic factor for the migration of these leukocytes to the brain. CCL6 may be a mediator released by microglia for cell-cell communication under physiological as well as pathological conditions of CNS. Additionally, the chemokine CCL6 may alter tumor behAvior by relieving its growth factor dependency and by promoting invasiveness as a result of local tissue apoptosis. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 12 kDa |