Mouse Activin A Protein
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产品编号
KMP3804
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别名
激活素, Activin A Protein, Mouse Activin A Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 激活素, Activin A Protein, Mouse Activin A Protein |
Catalog Number | KMP3804 |
Product Description | The Mouse Activin A Protein(KMP3804) is produced in HEK293 Cells. A DNA sequence encoding the Human/Mouse/Rat/Cynomolgus/Rhesus INHBA (NP_002183.1) (Gly311-Ser426) is expressed. |
Molecular Name | Activin A |
Species | Mouse |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <0.01 EU/ug determined by the LAL method |
Formulation | 4mM HCl |
Background | Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. Also, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in the epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 13 kDa |