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Cynomolgus TNFSF12 Protein, mFc Tag

Cynomolgus TNFSF12 Protein, mFc Tag

产品编号

KMP3799

别名

TNF超家族成员12, TNFSF12 Protein, Cynomolgus TNFSF12 Protein, mFc Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasTNF超家族成员12, TNFSF12 Protein, Cynomolgus TNFSF12 Protein, mFc Tag
Catalog NumberKMP3799
Product DescriptionThe Cynomolgus TNFSF12 Protein(KMP3799) is produced in HEK293 Cells. A DNA sequence encoding the human/Cynomolgus TNFSF12 (F7HGN4) (Ser94-His249) is expressed with the Fc region of Mouse IgG1 at the N-terminus. Human and Cynomolgus TNFSF12 sequences are identical.
Molecular NameTNFSF12
SpeciesCynomolgus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight43.8 kDa

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