Cynomolgus CD39 Protein, His Tag_天津卡梅德科技发展有限公司

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Cynomolgus CD39 Protein, His Tag

Cynomolgus CD39 Protein, His Tag

产品编号

KMP3769

别名

外核苷三磷酸二磷酸水解酶-1, CD39 Protein, Cynomolgus CD39 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	外核苷三磷酸二磷酸水解酶-1, CD39 Protein, Cynomolgus CD39 Protein, His Tag
Catalog Number	KMP3769
Product Description	The Cynomolgus CD39 Protein(KMP3769) is produced in Insect Cells. A DNA sequence encoding the Cynomolgus/Rhesus ENTPD1 (XP_015311944.1/XP_015003298.1) (Thr60-Val500) is expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus ENTPD1 sequences are identical.
Molecular Name	CD39
Species	Cynomolgus
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 300mM NaCl, 10% Glycerol, pH7.5
Background	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	51.8 kDa

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