Cynomolgus TNF-alpha Protein
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产品编号
KMP3756
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别名
肿瘤坏死因子α, TNF-alpha Protein, Cynomolgus TNF-alpha Protein
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规格
- 50ug
- 100ug
- 200ug
Alias | 肿瘤坏死因子α, TNF-alpha Protein, Cynomolgus TNF-alpha Protein |
Catalog Number | KMP3756 |
Product Description | The Cynomolgus TNF-alpha Protein(KMP3756) is produced in E. coli. A DNA sequence encoding the Cynomolgus/Rhesus TNF [(Identical to the Rhesus TNF (NP_001040614.1)] (Val77-Leu233) is expressed and purified with an initial Met. Cynomolgus and Rhesus TNF sequences are identical. |
Molecular Name | TNF-alpha |
Species | Cynomolgus |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 50mM Tris, 50mM NaCl, pH8.0 |
Background | Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & Antibody |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 17.4 kDa |