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Cynomolgus LIV-1 Protein, His Tag

Cynomolgus LIV-1 Protein, His Tag

产品编号

KMP3737

别名

锌转运体ZIP6, LIV-1 Protein, Cynomolgus LIV-1 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias锌转运体ZIP6, LIV-1 Protein, Cynomolgus LIV-1 Protein, His Tag
Catalog NumberKMP3737
Product DescriptionThe Cynomolgus LIV-1 Protein(KMP3737) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus SLC39A6 (A0A2K5WH46-1) (Met1-Gln308) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameLIV-1
SpeciesCynomolgus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM MES, 150mM NaCl, 10% Glycerol, 0.02% Tween80, pH6.0
BackgroundAlong with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight34 kDa

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