Cynomolgus TACI Protein, His Tag
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产品编号
KMP3736
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别名
跨膜激活物、钙调节物、亲环蛋白配体相互作用物, TACI Protein, Cynomolgus TACI Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 跨膜激活物、钙调节物、亲环蛋白配体相互作用物, TACI Protein, Cynomolgus TACI Protein, His Tag |
Catalog Number | KMP3736 |
Product Description | The Cynomolgus TACI Protein(KMP3736) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus TNFRSF13B (A0A2K5VNU0-1) (Ser2-Leu160) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | TACI |
Species | Cynomolgus |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF13B is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. TACI/TNFRSF13B/CD267 induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 19.2 kDa |