Cynomolgus CD96 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Cynomolgus CD96 Protein, His Tag, Avi Tag

Cynomolgus CD96 Protein, His Tag, Avi Tag

产品编号

KMP3735

别名

T细胞表面蛋白触觉, CD96 Protein, Cynomolgus CD96 Protein, His Tag, Avi Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	T细胞表面蛋白触觉, CD96 Protein, Cynomolgus CD96 Protein, His Tag, Avi Tag
Catalog Number	KMP3735
Product Description	The Cynomolgus CD96 Protein(KMP3735) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CD96 (A0A2K5TWV6-1) (Met1-Met503) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	CD96
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. The CD155 ligand CD96 is a member of the Ig superfamily. It's an immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), a nectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. The effect the cells with mutated CD96 protein lost adhesion and growth activities indicates that CD96 mutations may cause a form of the C syndrome by interfering with cell adhesion and growth.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	56.6 kDa

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