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Cynomolgus IL11 Protein

Cynomolgus IL11 Protein

产品编号

KMP3720

别名

白细胞介素11, IL11 Protein, Cynomolgus IL11 Protein

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞介素11, IL11 Protein, Cynomolgus IL11 Protein
Catalog NumberKMP3720
Product DescriptionThe Cynomolgus IL11 Protein(KMP3720) is produced in E. coli. A DNA sequence encoding the Cynomolgus IL11 (XP_005595839.2) (Phe22-Leu199) is expressed.
Molecular NameIL11
SpeciesCynomolgus
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 50mM NaCl, pH8.3
BackgroundIL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight19.39 kDa

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