Cynomolgus IL-1 RL1 Protein, His Tag_天津卡梅德科技发展有限公司

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Cynomolgus IL-1 RL1 Protein, His Tag

Cynomolgus IL-1 RL1 Protein, His Tag

产品编号

KMP3718

别名

白介素1受体样蛋白1, IL-1 RL1 Protein, Cynomolgus IL-1 RL1 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白介素1受体样蛋白1, IL-1 RL1 Protein, Cynomolgus IL-1 RL1 Protein, His Tag
Catalog Number	KMP3718
Product Description	The Cynomolgus IL-1 RL1 Protein(KMP3718) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus IL1RL1 (XP_005575214.1) (Met1-Cys331) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	IL-1 RL1
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	37.1 kDa

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