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Cynomolgus IL4R Protein, His Tag

Cynomolgus IL4R Protein, His Tag

产品编号

KMP3710

别名

白细胞介素4受体, IL4R Protein, Cynomolgus IL4R Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞介素4受体, IL4R Protein, Cynomolgus IL4R Protein, His Tag
Catalog NumberKMP3710
Product DescriptionThe Cynomolgus IL4R Protein(KMP3710) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus IL4R (EHH60265.1) (Met1-Arg232) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameIL4R
SpeciesCynomolgus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behAvior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD124, also known as the interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to a soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight25.2 kDa

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