Cynomolgus CD147 Protein, His Tag_天津卡梅德科技发展有限公司

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Cynomolgus CD147 Protein, His Tag

Cynomolgus CD147 Protein, His Tag

产品编号

KMP3688

别名

肿瘤细胞衍生的胶原酶刺激因子, CD147 Protein, Cynomolgus CD147 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤细胞衍生的胶原酶刺激因子, CD147 Protein, Cynomolgus CD147 Protein, His Tag
Catalog Number	KMP3688
Product Description	The Cynomolgus CD147 Protein(KMP3688) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CD147 (XP_005587354.1) (Met1-His209) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CD147
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	21.4 kDa

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