Cynomolgus CD2 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Cynomolgus CD2 Protein, hFc Tag

Cynomolgus CD2 Protein, hFc Tag

产品编号

KMP3680

别名

T细胞表面抗原 CD2, CD2 Protein, Cynomolgus CD2 Protein, hFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	T细胞表面抗原 CD2, CD2 Protein, Cynomolgus CD2 Protein, hFc Tag
Catalog Number	KMP3680
Product Description	The Cynomolgus CD2 Protein(KMP3680) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CD2 (Q6SZ61) (Met1-Asp209) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	CD2
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	48.1 kDa

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