Cynomolgus CD8 beta Protein, hFc Tag
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产品编号
KMP3664
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别名
T细胞表面糖蛋白CD8β链, CD8 beta Protein, Cynomolgus CD8 beta Protein, hFc Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | T细胞表面糖蛋白CD8β链, CD8 beta Protein, Cynomolgus CD8 beta Protein, hFc Tag |
Catalog Number | KMP3664 |
Product Description | The Cynomolgus CD8 beta Protein(KMP3664) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CD8B (XP_005575417.1) (Met1-Pro170) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | CD8 beta |
Species | Cynomolgus |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. CD8 is thought to play a role in the process of T-cell mediated killing. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 43.88 kDa |