Cynomolgus TNFSF4 Protein, mFc Tag_天津卡梅德科技发展有限公司

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Cynomolgus TNFSF4 Protein, mFc Tag

Cynomolgus TNFSF4 Protein, mFc Tag

产品编号

KMP3654

别名

肿瘤坏死因子配体超家族成员4, TNFSF4 Protein, Cynomolgus TNFSF4 Protein, mFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子配体超家族成员4, TNFSF4 Protein, Cynomolgus TNFSF4 Protein, mFc Tag
Catalog Number	KMP3654
Product Description	The Cynomolgus TNFSF4 Protein(KMP3654) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus TNFSF4 (F7FL80) (Gln51-Leu183) is expressed with the Fc region of Mouse IgG1 at the N-terminus.
Molecular Name	TNFSF4
Species	Cynomolgus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD4-stimulated B cells, this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	42 kDa

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