Cynomolgus BCA-1 Protein, His Tag_天津卡梅德科技发展有限公司

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Cynomolgus BCA-1 Protein, His Tag

Cynomolgus BCA-1 Protein, His Tag

产品编号

KMP3648

别名

C-C基序趋化因子-13, BCA-1 Protein, Cynomolgus BCA-1 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	C-C基序趋化因子-13, BCA-1 Protein, Cynomolgus BCA-1 Protein, His Tag
Catalog Number	KMP3648
Product Description	The Cynomolgus BCA-1 Protein(KMP3648) is produced in E. coli. A DNA sequence encoding the mature form of Cynomolgus (Macaca fascicularis) CXCL13 (Val 23-Pro 109) is expressed, with an N-terminal polyhistidine tag.
Molecular Name	BCA-1
Species	Cynomolgus
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	10mM Tris, 250mM NaCl, pH8.0
Background	The chemokine CXCL13, also known as BCA-1 (B-cell-attracting chemokine-1) or BLC (B-lymphocyte chemoattractant), which belongs to the CXC chemokine family. CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. CXCL13 is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation. It involves in B-cell compartmental homing within secondary lymphoid organs and recently implicated in the pathogenesis of inflammatory and malignant lymphocyte-mediated diseases. In Primary central nervous system lymphoma (PCNSL), expression of BCA-1 by malignant lymphocytes and vascular endothelium may influence tumor development and localization to central nervous system (CNS). In T-lymphocytes, CXCL13 expression is thought to reflect a germinal center origin of the T-cell. CXCL13 expression may also provide an additional useful tool for the diagnosis of Angioimmunoblastic T-cell lymphoma (AITL).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	12.4 kDa

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