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Cynomolgus IL-13 Protein, His Tag

Cynomolgus IL-13 Protein, His Tag

产品编号

KMP3644

别名

白细胞介素-13, IL-13 Protein, Cynomolgus IL-13 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞介素-13, IL-13 Protein, Cynomolgus IL-13 Protein, His Tag
Catalog NumberKMP3644
Product DescriptionThe Cynomolgus IL-13 Protein(KMP3644) is produced in HEK293 Cells. A DNA sequence encoding the mature form of Cynomolgus (Macaca fascicularis) IL-13 (ABG75889.1) (Ser 21-Asn 132) is fused with a polyhistidine tag at the N-terminus.
Molecular NameIL-13
SpeciesCynomolgus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundInterleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight14.5 kDa

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