Cynomolgus IL-13 Protein, His Tag
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产品编号
KMP3644
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别名
白细胞介素-13, IL-13 Protein, Cynomolgus IL-13 Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞介素-13, IL-13 Protein, Cynomolgus IL-13 Protein, His Tag |
Catalog Number | KMP3644 |
Product Description | The Cynomolgus IL-13 Protein(KMP3644) is produced in HEK293 Cells. A DNA sequence encoding the mature form of Cynomolgus (Macaca fascicularis) IL-13 (ABG75889.1) (Ser 21-Asn 132) is fused with a polyhistidine tag at the N-terminus. |
Molecular Name | IL-13 |
Species | Cynomolgus |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 14.5 kDa |