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Chinese Hamster Clusterin Protein, His Tag

Chinese Hamster Clusterin Protein, His Tag

产品编号

KMP3639

别名

丛生蛋白, Clusterin Protein, Chinese Hamster Clusterin Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias丛生蛋白, Clusterin Protein, Chinese Hamster Clusterin Protein, His Tag
Catalog NumberKMP3639
Product DescriptionThe Chinese Hamster Clusterin Protein(KMP3639) is produced in CHO Cells. A DNA sequence encoding the Chinese Hamster CLU (G3HNJ3-1) (Glu22-Glu447) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameClusterin
SpeciesChinese Hamster
HostCHO Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundClusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight50.9 kDa

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