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Chinese Hamster PLBD2 Protein, His Tag

Chinese Hamster PLBD2 Protein, His Tag

产品编号

KMP3638

别名

含磷脂酶B结构域2, PLBD2 Protein, Chinese Hamster PLBD2 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias含磷脂酶B结构域2, PLBD2 Protein, Chinese Hamster PLBD2 Protein, His Tag
Catalog NumberKMP3638
Product DescriptionThe Chinese Hamster PLBD2 Protein(KMP3638) is produced in CHO Cells. A DNA sequence encoding the Chinese Hamster PLBD2 (G3I6T1-1) (Leu38-Asp585) is expressed with a polyhistidine tag at the C-terminus.
Molecular NamePLBD2
SpeciesChinese Hamster
HostCHO Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundPLBD2 localizes to the lysosome, as its absence could plausibly lead to a serious yet unrecognized lysosomal storage disease. PLBD1 and PLBD2 are semi-orphans in the sense of being probable phospholipases of B class but with uncertain physiological substrates and thus functionalities. PLBD1 and PLBD2 constitute a small gene family (sequence homology class) within vertebrates though one that occurs expanded in some early diverging eukaryotes. PLBD2 presents a special difficulty in that a sequence of post-translational steps are apparently necessary for its activation. Without these, potential substrates can hardly be assayed. These steps include removal of the signal peptide, mannosylation appropriate to the lysosome targeting receptor, and self-catalytic proteolytic activation to expose the substrate binding site as this becomes appropriate.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight63.3 kDa

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