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Canine Canf4 Protein, His Tag

Canine Canf4 Protein, His Tag

产品编号

KMP3632

别名

过敏原蛋白Can f 4, Canf4 Protein, Canine Canf4 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias过敏原蛋白Can f 4, Canf4 Protein, Canine Canf4 Protein, His Tag
Catalog NumberKMP3632
Product DescriptionThe Canine Canf4 Protein(KMP3632) is produced in HEK293 Cells. A DNA sequence encoding the Canine Canf4 (NP_001177855.1) (Met1-Glu174) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameCanf4
SpeciesCanine
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 100mM NaCl, 0.02% Tween80, pH8.0
BackgroundDog dander is an important cause of respiratory allergy but its content of allergenic components is still incompletely known. The size and the amino acid composition of the ligand-binding pocket indicate that Can f 4 is capable of binding only relatively small hydrophobic molecules which are different from those that Can f 2 is able to bind. The crystal structure of Can f 4 contained both monomeric and dimeric forms of the allergen, suggesting that Can f 4 is able to form transient (weak) dimers. The existence of transient dimers in solution was confirmed by use of native mass spectrometry. The dimeric structure of Can f 4 is formed when the ends of four β-strands are packed against the same strands from the second monomer.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight19.1 kDa

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