Canine KIM-1 Protein, mFc Tag_天津卡梅德科技发展有限公司

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Canine KIM-1 Protein, mFc Tag

Canine KIM-1 Protein, mFc Tag

产品编号

KMP3596

别名

肾损伤分子-1, KIM-1 Protein, Canine KIM-1 Protein, mFc Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肾损伤分子-1, KIM-1 Protein, Canine KIM-1 Protein, mFc Tag
Catalog Number	KMP3596
Product Description	The Canine KIM-1 Protein(KMP3596) is produced in HEK293 Cells. A DNA sequence encoding the extracellular domain of Canine HAVCR1 (XP_854888.1) (Tyr21-Ser160) is fused with the Fc region of Mouse IgG at the N-terminus.
Molecular Name	KIM-1
Species	Canine
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	41.8 kDa

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