Human IFN gamma Protein_天津卡梅德科技发展有限公司

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Human IFN gamma Protein

Human IFN gamma Protein

产品编号

KMP3580

别名

干扰素-γ, Human IFN gamma Protein, IFN gamma

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	干扰素-γ, Human IFN gamma Protein, IFN gamma
Catalog Number	KMP3580
Product Description	The Human IFN gamma Protein(KMP3580) is produced in E. coli. The target gene encoding the human IFNG (NP_000610.2) (Gln24-Gln166) is expressed.
Molecular Name	IFN gamma
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<5.0 EU/mg determined by the LAL method
Formulation	50mM Tris, pH8.0
Background	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to hAving antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	16.91 kDa

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