Human Activin A Protein_天津卡梅德科技发展有限公司

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Human Activin A Protein

Human Activin A Protein

产品编号

KMP3574

别名

激活素A, Human Activin A Protein, Activin A

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	激活素A, Human Activin A Protein, Activin A
Catalog Number	KMP3574
Product Description	The Human Activin A Protein(KMP3574) is produced in HEK293 Cells. The target gene encoding the Human / Mouse / Rat / Cynomolgus / Rhesus INHBA (NP_002183.1) (Gly311-Ser426) is expressed.
Molecular Name	Activin A
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<0.01 EU/ug determined by the LAL method
Formulation	4mM HCl
Background	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. Also, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in the epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	13 kDa

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