Human IL-6 Protein_天津卡梅德科技发展有限公司

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Human IL-6 Protein

Human IL-6 Protein

产品编号

KMP3573

别名

白介素6, Human IL-6 Protein, IL-6

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白介素6, Human IL-6 Protein, IL-6
Catalog Number	KMP3573
Product Description	The Human IL-6 Protein(KMP3573) is produced in E. coli. The target gene encoding the mature form of human IL6 (NP_000591.1) (Val30-Met212) is expressed with an initial Met at the N-terminus.
Molecular Name	IL-6
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<5.0 EU/mg determined by the LAL method
Formulation	PBS, pH7.4
Background	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	20.95 kDa

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