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Human IL-1 beta Protein

Human IL-1 beta Protein

产品编号

KMP3570

别名

白细胞介素-1β, Human IL-1 beta Protein, IL-1 beta

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞介素-1β, Human IL-1 beta Protein, IL-1 beta
Catalog NumberKMP3570
Product DescriptionThe Human IL-1 beta Protein(KMP3570) is produced in E. coli. The target gene encoding the mature form of human IL1B (NP_000567.1) (Ala 117-Ser 269) is expressed with a N-terminal Met.
Molecular NameIL-1 beta
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<5.0 EU/mg determined by the LAL method
FormulationPBS, pH7.4
BackgroundInterleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight17.5 kDa

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