Human IL15 & IL15RA Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human IL15 & IL15RA Protein, hFc Tag

Human IL15 & IL15RA Protein, hFc Tag

产品编号

KMP3556

别名

IL15和IL15RA的异二聚体蛋白, Human IL15 & IL15RA Protein, hFc Tag, IL15 & IL15RA

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	IL15和IL15RA的异二聚体蛋白, Human IL15 & IL15RA Protein, hFc Tag, IL15 & IL15RA
Catalog Number	KMP3556
Product Description	The Human IL15 & IL15RA Protein(KMP3556) is produced in HEK293 Cells. The target gene encoding the human IL15RA (NP_002180.1) (Ile31-Asp96) linked with the human IL15 (NP_000576.1, with mutation Asn 120 Asp) (Asn49-Ser162) by a peptide linker is fused with the Fc region of human IgG1 at the C-terminus.
Molecular Name	IL15 & IL15RA
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	50mM Tris, 100mM NaCl, 5% Trehalose, 0.05% Chaps, pH8.5
Background	IL-15 and IL-15 receptor alpha (IL-15Rα) play a significant role in multiple aspects of T cell biology. Interleukin (IL)-15 is essential for natural killer (NK), NKT and memory (m) CD8+ T cell development and function, and is currently under investigation as an immunotherapeutic agent for the treatment of cancer. Recently, the creation of IL-15 superagonist by complexing IL-15 and its high affinity receptor alpha (IL-15 Rα) in solution, inspired by the natural trans-presentation of IL-15, advances the potential of IL-15-based tumor immunotherapy. Gene therapy using engineered cells co-expressing IL-15/IL-15 Rα complex for cancer treatment is also emerging.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	47.9 kDa

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