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Human CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag

Human CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag

产品编号

KMP3552

别名

CD8A和CD8B的异二聚体蛋白, Human CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag, CD8A & CD8B Heterodimer

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasCD8A和CD8B的异二聚体蛋白, Human CD8A & CD8B Heterodimer Protein, Flag Tag, His Tag, CD8A & CD8B Heterodimer
Catalog NumberKMP3552
Product DescriptionThe Human CD8A & CD8B Heterodimer Protein(KMP3552) is produced in HEK293 Cells. The target gene encoding the human CD8A (NP_001759.3) (Met1-Asp182) is fused with a flag tag at the C-terminus, constructed the plasmid 1; The target gene encoding the human CD8B (NP_004922.1) (Met1-Pro170) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the human CD8A&CD8B heterodimer is purified.
Molecular NameCD8A & CD8B Heterodimer
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD8A (CD8 Subunit Alpha) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Herpes Zoster. Among its related pathways are TCR Signaling (Qiagen) and Network map of SARS-CoV-2 signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity. CD8B (CD8 Subunit Beta) is a Protein Coding gene. Diseases associated with CD8B include Diffuse Large B-Cell Lymphoma and Uterine Corpus Cancer. Among its related pathways are Infectious disease and Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters. Gene Ontology (GO) annotations related to this gene include coreceptor activity and MHC class I protein binding. An important paralog of this gene is CD8B2.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight44.1 kDa

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