Human IL-12 Protein, His Tag
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产品编号
KMP3536
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别名
白细胞介素, Human IL-12 Protein, His Tag, IL-12
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规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞介素, Human IL-12 Protein, His Tag, IL-12 |
Catalog Number | KMP3536 |
Product Description | The Human IL-12 Protein(KMP3536) is produced in HEK293 Cells. The target gene encoding the p35 subunit of human IL-12, termed as IL12A (P29459.2) (Met1-Ser219) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1 ; The target gene encoding the p40 subunit of human IL-12, termed as IL12B (NP_002178.2) (Met1-Ser328) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the heterodimer is purified. The purified protein is biotinylated in vitro. |
Molecular Name | IL-12 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | IL12A (Interleukin 12A) is a Protein Coding gene. Diseases associated with IL12A include Behcet Syndrome and Primary Biliary Cholangitis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and growth factor activity. IL12B (Interleukin 12B) is a Protein Coding gene. Diseases associated with IL12B include Immunodeficiency 29 and Takayasu Arteritis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 60.13 kDa |