Human TNFSF12 Protein, mFc Tag_天津卡梅德科技发展有限公司

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Human TNFSF12 Protein, mFc Tag

Human TNFSF12 Protein, mFc Tag

产品编号

KMP3532

别名

肿瘤坏死因子超家族成员12, Human TNFSF12 Protein, mFc Tag, TNFSF12

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子超家族成员12, Human TNFSF12 Protein, mFc Tag, TNFSF12
Catalog Number	KMP3532
Product Description	The Human TNFSF12 Protein(KMP3532) is produced in HEK293 Cells. The target gene encoding the human / cynomolgus TNFSF12 (F7HGN4) (Ser94-His249) is expressed with the Fc region of mouse IgG1 at the N-terminus. Human and Cynomolgus TNFSF12 sequences are identical.
Molecular Name	TNFSF12
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	43.8 kDa

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