Human EGFR Protein, His Tag_天津卡梅德科技发展有限公司

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Human EGFR Protein, His Tag

Human EGFR Protein, His Tag

产品编号

KMP3475

别名

表皮生长因子受体, Human EGFR Protein, His Tag, EGFR

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	表皮生长因子受体, Human EGFR Protein, His Tag, EGFR
Catalog Number	KMP3475
Product Description	The Human EGFR Protein(KMP3475) is produced in HEK293 Cells. The target gene encoding the human EGFR (NP_001333870.1, Isoform vIII) (Met1-Ser378) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	EGFR
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	40.09 kDa

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