Human GPRC5D Protein_天津卡梅德科技发展有限公司

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Human GPRC5D Protein

Human GPRC5D Protein

产品编号

KMP3463

别名

G蛋白偶联受体家族C组5成员D, Human GPRC5D Protein, GPRC5D

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	G蛋白偶联受体家族C组5成员D, Human GPRC5D Protein, GPRC5D
Catalog Number	KMP3463
Product Description	The Human GPRC5D Protein(KMP3463) is produced in HEK293 Cells. The target gene encoding the human GPRC5D (Q9NZD1-1) (Met1-Val345) is expressed.
Molecular Name	GPRC5D
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	50mM HEPES, 150mM NaCl, 10% Trehalose, pH7.2
Background	Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	38.80 kDa

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