Human CCK4 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CCK4 Protein, His Tag

Human CCK4 Protein, His Tag

产品编号

KMP3440

别名

蛋白酪氨酸激酶7, Human CCK4 Protein, His Tag, CCK4

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	蛋白酪氨酸激酶7, Human CCK4 Protein, His Tag, CCK4
Catalog Number	KMP3440
Product Description	The Human CCK4 Protein(KMP3440) is produced in HEK293 Cells. The target gene encoding the human PTK7 (NP_002812.2) (Met1-Thr704) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CCK4
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. On a cellular level PTK7 affects the establishment of cell polarity, the regulation of cell movement and migration as well as cell invasion. The PTK7 receptor interacts with ligands, co-receptors, and intracellular transducers of Wnt signaling pathways, pointing to a function in the fine-tuning of the Wnt signaling network. PTK7 is a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. PTK7 plays an important role in human cancers, including triple-negative breast cancer (TNBC), ovarian cancer, and non-small cell lung cancer (NSCLC).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	76.1 kDa

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