Human CD57 Protein, mFc Tag
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产品编号
KMP3433
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别名
β-1,3-葡萄糖醛酸转移酶1, Human CD57 Protein, mFc Tag, CD57
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规格
- 50ug
- 100ug
- 200ug
Alias | β-1,3-葡萄糖醛酸转移酶1, Human CD57 Protein, mFc Tag, CD57 |
Catalog Number | KMP3433 |
Product Description | The Human CD57 Protein(KMP3433) is produced in HEK293 Cells. The target gene encoding the human B3GAT1 (NP_473366.1) (Thr28-Ile334) is expressed with the Fc region of mouse IgG1 at the N-terminus. |
Molecular Name | CD57 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited downstream integrin signaling, which was mimicked by knockdown of the core chondroitin sulfate synthesis enzymes β-1,3-glucuronyltransferase 1 (B3GAT1) and chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1). |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 61.7 kDa |