Human SFTPB Protein, His Tag_天津卡梅德科技发展有限公司

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Human SFTPB Protein, His Tag

Human SFTPB Protein, His Tag

产品编号

KMP3425

别名

表面活性蛋白 B, Human SFTPB Protein, His Tag, SFTPB

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	表面活性蛋白 B, Human SFTPB Protein, His Tag, SFTPB
Catalog Number	KMP3425
Product Description	The Human SFTPB Protein(KMP3425) is produced in CHO Cells. The target gene encoding the Human SFTPB (NP_000533.4) (Trp25-Ser381) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	SFTPB
Species	Human
Host	CHO Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Pulmonary surfactant-associated protein B, also known as SFTPB and SP-B, contains one saposin A-type domain and three saposin B-type domains. SP-B is produced primarily by alveolar type II cells (AEC2) but also by nonciliated respiratory epithelial cells lining distal portions of the respiratory tract. Its secretion promotes alveolar homeostasis, stabilizing lipid layers and lowering surface tension at the air-liquid interface in the peripheral air spaces. Alveolar SP-B influences surfactant formation, effector cell functions, and innate host defense. Deficiency is associated with respiratory distress syndrome (RDS), pulmonary surfactant metabolism dysfunction 1 (SMDP1), and other human lung diseases. Gene addition and editing therapies show promise by complementing SP-B expression in AEC2s, restoring the phenotypic defect in vitro and in vivo.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	41.04 kDa

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