首页
>>
产品中心
>>
蛋白产品
>>
重组蛋白
>
Human AMH Protein, His Tag

Human AMH Protein, His Tag

产品编号

KMP3421

别名

抗缪勒氏管激素, Human AMH Protein, His Tag, AMH

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias抗缪勒氏管激素, Human AMH Protein, His Tag, AMH
Catalog NumberKMP3421
Product DescriptionThe Human AMH Protein(KMP3421) is produced in HEK293 Cells. The target gene encoding the human AMH (NP_000470.2) (Leu25-Arg560) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameAMH
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 150mM NaCl, pH8.0
BackgroundAnti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and this process involves the SOX9 transcription factor. AMH is widely used for assessing ovarian reserve, and it is particularly convenient, because it is thought to have minimal variability throughout the menstrual cycle. Fetal anti-Mullerian hormone (AMH) is responsible for normal male sexual differentiation, and circulating AMH is used as a marker of testicular tissue in newborns with disorders of sex development. Anti-Mullerian hormone (AMH) produced in the developing testis induces the regression of the Mullerian duct, which develops into the oviducts, uterus and upper vagina. As well as other hormone receptors, and a decreased ovarian cortex cell proliferation. These results help understand the inhibitory effects of AMH on follicular development.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight59.1 kDa

登录

还没有账号?立即注册

注册

已有账号?立即登录

立即询价