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Human TSHR Protein, His Tag

Human TSHR Protein, His Tag

产品编号

KMP3416

别名

人促甲状腺激素受体, Human TSHR Protein, His Tag, TSHR

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias人促甲状腺激素受体, Human TSHR Protein, His Tag, TSHR
Catalog NumberKMP3416
Product DescriptionThe Human TSHR Protein(KMP3416) is produced in Insect Cells. The target gene encoding the human TSHR (NP_000360.2) (Gly21-Gly413) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameTSHR
SpeciesHuman
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 150mM NaCl, 10% Glycerol, 1mM TCEP, pH7.5
BackgroundThyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight46.1 kDa

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