Human TL1A Protein, rFc Tag
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产品编号
KMP3407
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别名
肿瘤坏死因子超家族成员15, Human TL1A Protein, rFc Tag, TL1A
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规格
- 50ug
- 100ug
- 200ug
Alias | 肿瘤坏死因子超家族成员15, Human TL1A Protein, rFc Tag, TL1A |
Catalog Number | KMP3407 |
Product Description | The Human TL1A Protein(KMP3407) is produced in HEK293 Cells. The target gene encoding the human TNFSF15 (NP_005109.2) (Leu72-Leu251) is expressed with the Fc region of rabbit IgG at the N-terminus.. |
Molecular Name | TL1A |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 48 kDa |