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Human TL1A Protein, rFc Tag

Human TL1A Protein, rFc Tag

产品编号

KMP3407

别名

肿瘤坏死因子超家族成员15, Human TL1A Protein, rFc Tag, TL1A

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子超家族成员15, Human TL1A Protein, rFc Tag, TL1A
Catalog NumberKMP3407
Product DescriptionThe Human TL1A Protein(KMP3407) is produced in HEK293 Cells. The target gene encoding the human TNFSF15 (NP_005109.2) (Leu72-Leu251) is expressed with the Fc region of rabbit IgG at the N-terminus..
Molecular NameTL1A
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight48 kDa

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