Human CD45 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD45 Protein, His Tag

Human CD45 Protein, His Tag

产品编号

KMP3397

别名

白细胞共同抗原, Human CD45 Protein, His Tag, CD45

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞共同抗原, Human CD45 Protein, His Tag, CD45
Catalog Number	KMP3397
Product Description	The Human CD45 Protein(KMP3397) is produced in HEK293 Cells. The target gene encoding the human PTPRC (XP_006711535.1) (Met1-Lys529) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CD45
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	57.4 kDa

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