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Human SYAP1 Protein, His Tag

Human SYAP1 Protein, His Tag

产品编号

KMP3395

别名

突触相关蛋白 1, Human SYAP1 Protein, His Tag, SYAP1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias突触相关蛋白 1, Human SYAP1 Protein, His Tag, SYAP1
Catalog NumberKMP3395
Product DescriptionThe Human SYAP1 Protein(KMP3395) is produced in Insect Cells. The target gene encoding the Human SYAP1 (NP_116185.2) (Met1-Asn352) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameSYAP1
SpeciesHuman
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM PB, 300mM NaCl, 10% Glycerol, 1mM TCEP, pH7.0
BackgroundSynapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the C-terminus. Expressed near neuronal Golgi and synaptic regions of cerebellar Purkinje cells, SYAP1 has been linked to intact sensorimotor control and general vesicular trafficking in neurons. SYAP1-deficient mice display impaired locomotor activity. In cultured adipocytes, SYAP1 facilitates mTORC2-mediated phosphorylation of protein kinase Akt1 and adipocyte differentiation. Chromosomal band Xp22.2 houses the human SYAP1 gene, a region associated with developmental delay and autism spectrum disorder. SYAP 1 may be a target for future cancer therapies as it was induced by tamoxifen in breast cancer cells sensitive to tamoxifen growth inhibition.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight41.39 kDa

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