Human SYAP1 Protein, His Tag
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产品编号
KMP3395
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别名
突触相关蛋白 1, Human SYAP1 Protein, His Tag, SYAP1
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规格
- 50ug
- 100ug
- 200ug
Alias | 突触相关蛋白 1, Human SYAP1 Protein, His Tag, SYAP1 |
Catalog Number | KMP3395 |
Product Description | The Human SYAP1 Protein(KMP3395) is produced in Insect Cells. The target gene encoding the Human SYAP1 (NP_116185.2) (Met1-Asn352) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | SYAP1 |
Species | Human |
Host | Insect Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 20mM PB, 300mM NaCl, 10% Glycerol, 1mM TCEP, pH7.0 |
Background | Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the C-terminus. Expressed near neuronal Golgi and synaptic regions of cerebellar Purkinje cells, SYAP1 has been linked to intact sensorimotor control and general vesicular trafficking in neurons. SYAP1-deficient mice display impaired locomotor activity. In cultured adipocytes, SYAP1 facilitates mTORC2-mediated phosphorylation of protein kinase Akt1 and adipocyte differentiation. Chromosomal band Xp22.2 houses the human SYAP1 gene, a region associated with developmental delay and autism spectrum disorder. SYAP 1 may be a target for future cancer therapies as it was induced by tamoxifen in breast cancer cells sensitive to tamoxifen growth inhibition. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 41.39 kDa |