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Human ILT3 Protein, His Tag

Human ILT3 Protein, His Tag

产品编号

KMP3393

别名

白细胞免疫球蛋白样受体 B4, Human ILT3 Protein, His Tag, ILT3

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞免疫球蛋白样受体 B4, Human ILT3 Protein, His Tag, ILT3
Catalog NumberKMP3393
Product DescriptionThe Human ILT3 Protein(KMP3393) is produced in HEK293 Cells. The target gene encoding the human LILRB4 (AAH26309.1) (Met1-Glu259) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro.
Molecular NameILT3
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundLILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight27.7 kDa

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