Human ILT3 Protein, hFc Tag
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产品编号
KMP3391
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别名
白细胞免疫球蛋白样受体 B4, Human ILT3 Protein, hFc Tag, ILT3
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规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞免疫球蛋白样受体 B4, Human ILT3 Protein, hFc Tag, ILT3 |
Catalog Number | KMP3391 |
Product Description | The Human ILT3 Protein(KMP3391) is produced in HEK293 Cells. The target gene encoding the human LILRB4 (NP_001265356.2) (Met1-His257) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | ILT3 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases. The LILRB4 is a central inhibitory receptor in Uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 52.8 kDa |