Human Claudin-6 Protein_天津卡梅德科技发展有限公司

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Human Claudin-6 Protein

Human Claudin-6 Protein

产品编号

KMP3390

别名

紧密连接蛋白6, Human Claudin-6 Protein, Claudin-6

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	紧密连接蛋白6, Human Claudin-6 Protein, Claudin-6
Catalog Number	KMP3390
Product Description	The Human Claudin-6 Protein(KMP3390) is produced in HEK293 Cells. The target gene encoding the human CLDN6 (P56747) (Met1-Val220) is expressed. THis protein carries a GFP tag.
Molecular Name	Claudin-6
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	50mM HEPES, 150mM NaCl, 10% Trehalose, pH7.2
Background	Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	50.31 kDa

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