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Human TFF3 Protein, His Tag

Human TFF3 Protein, His Tag

产品编号

KMP3386

别名

三叶因子3, Human TFF3 Protein, His Tag, TFF3

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias三叶因子3, Human TFF3 Protein, His Tag, TFF3
Catalog NumberKMP3386
Product DescriptionThe Human TFF3 Protein(KMP3386) is produced in HEK293 Cells. The target gene encoding the human TFF3 (NP_003217.3) (Met1-Phe94) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameTFF3
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTrefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types of cancer. The presence and localization of TFF3 peptide was associated with the embryonic stage and tissue differentiation. TFF3 peptide distribution specific to the germ layers was not observed. The role of TFF3 peptide in cell migration and differentiation, immune response, and apoptosis might be associated with specific embryonic epithelial cells. TFF3 peptide may also be considered as a marker for mucosal maturation. Trefoil factor 3 (TFF3) serves an important role in intestinal mucosal damage and healing, and contributes to the pathogenesis and treatment of inflammatory bowel disease (IBD). The involvement of TFF3 in the pathogenesis of rhonchopathy and OSA and lead to the hypothesis that reduction of TFF3 production by the epithelium and subepithelial mucous glands of the uvula contributes to an increase in breathing resistance due to a change in mucus organization.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight8 kDa

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