Human NPC1 Protein, His Tag, Flag Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

Human NPC1 Protein, His Tag, Flag Tag

Human NPC1 Protein, His Tag, Flag Tag

产品编号

KMP3385

别名

细胞内胆固醇转运蛋白 1, Human NPC1 Protein, His Tag, FLAG Tag, NPC1

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	细胞内胆固醇转运蛋白 1, Human NPC1 Protein, His Tag, FLAG Tag, NPC1
Catalog Number	KMP3385
Product Description	The Human NPC1 Protein(KMP3385) is produced in HEK293 Cells. The target gene encoding the human NPC1 (NP_000262.2) (Arg372-Phe622) is expressed with a N-terminal polyHistide-tagged FLAG tag at the N-terminus (His-FLAG).
Molecular Name	NPC1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pick C1 (NPC1), a membrane protein of lysosomes, is required for the export of cholesterol derived from receptor-mediated endocytosis of LDL. The NPC1 protein is a multipass transmembrane protein whose deficiency causes the autosomal recessive lipid storage disorder Niemann-Pick type C1. NPC1 localizes predominantly to late endosomes and has a dileucine motif located within a small cytoplasmic tail thought to target the protein to this location. Niemann-Pick disease type C1 (NPC1) is a rare progressive neurodegenerative disorder caused by mutations in the NPC1 gene. On the cellular level, NPC1 mutations lead to an accumulation of cholesterol and gangliosides.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	32 kDa

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0