Human LAG3 Protein, mFc Tag_天津卡梅德科技发展有限公司

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Human LAG3 Protein, mFc Tag

Human LAG3 Protein, mFc Tag

产品编号

KMP3381

别名

淋巴细胞激活基因-3, Human LAG3 Protein, mFc Tag, LAG3

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	淋巴细胞激活基因-3, Human LAG3 Protein, mFc Tag, LAG3
Catalog Number	KMP3381
Product Description	The Human LAG3 Protein(KMP3381) is produced in HEK293 Cells. The target gene encoding the human LAG3 (NP_002277.4) (Met1-Leu450) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular Name	LAG3
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	72.6 kDa

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