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Human MTH1 Protein, His Tag

Human MTH1 Protein, His Tag

产品编号

KMP3372

别名

Nudix 水解酶, Human MTH1 Protein, His Tag, MTH1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasNudix 水解酶, Human MTH1 Protein, His Tag, MTH1
Catalog NumberKMP3372
Product DescriptionThe Human MTH1 Protein(KMP3372) is produced in E. coli. The target gene encoding the human NUDT1 (NP_002443.3) (Met1-Val156) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameMTH1
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 100mM NaCl, pH8.0
BackgroundNUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1 protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Cancers can survive the oxidative conditions by upregulating nucleoside diphosphate linked moiety X-type motif 1 (NUDT1). MiR-485-5p acts as a tumor suppressor by targeting NUDT1 in gastric cancer (GC). The miR-485-5p/NUDT1 axis is involved in the processes of cell growth and cell motility and plays a key role in the tumorigenesis of GC.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight20.2 kDa

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