Human HHLA2 Protein, His Tag_天津卡梅德科技发展有限公司

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Human HHLA2 Protein, His Tag

Human HHLA2 Protein, His Tag

产品编号

KMP3365

别名

人内源性逆转录病毒-H长末端重复结合蛋白2 , Human HHLA2 Protein, His Tag, HHLA2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	人内源性逆转录病毒-H长末端重复结合蛋白2 , Human HHLA2 Protein, His Tag, HHLA2
Catalog Number	KMP3365
Product Description	The Human HHLA2 Protein(KMP3365) is produced in HEK293 Cells. The target gene encoding the human HHLA2 (NP_009003.1) (Met1-Asn344) is expressed with a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	HHLA2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants. HERV–H LTR-associating 2 (HHLA2, also called B7H7/B7-H5/B7y)has been recently discovered as the newest member of the B7 family and has 23–33% similarity in amino acid sequence with the other B7 molecules. This ligand is the only B7 family member that is found in humans but not in mice. It is constitutively expressed on the surface of human monocytes and is induced on B cells. HHLA2 binds to its putative receptor(s) on a variety of immune cells including CD4 and CD8 T cells and antigen-presenting cells. Similar to B7-H3, both a T cell coinhibitory role, as well as a costimulatory role, has been reported for this ligand.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	38.4 kDa

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